Listeria Monocytogenes Infection: A Comprehensive Overview
Epidemiology and Pathogenesis
Listeriosis, an infection caused by the gram-positive bacterium Listeria monocytogenes, poses a significant threat to public health. It accounts for approximately 1-2% of neonatal and 4-5% of adult bacterial meningitis cases.
Clinical Presentation
Listeriosis frequently manifests with encephalitic symptoms (87% present with nuchal rigidity), highlighting the neuroinvasive nature of the infection.
Treatment and Prognosis
The initial therapy for community-acquired bacterial meningitis, including Listeria meningitis, typically involves antibiotics. The treatment duration can vary significantly (10 days to 8 weeks) depending on the severity of the case.
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